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Phentermine is combined with diet and exercise for the short-term treatment of obesity in individuals with a body mass index greater than or equal to 30 kg/m2 or more than or equal to 27 kg/m2 with risk factors for cardiovascular diseases.
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Combining phentermine with tricyclic antidepressants or monoamine oxidase inhibitors may result in elevated blood pressure and other serious reactions because of elevated serotonin levels in the blood.

