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Studies of numerous variables has indicated that approximately 60% of patients who lose at least 4 pounds in the first 4 weeks of treatment with a given dose of this drug in combination with a reduced-calorie diet lose at least 5% (placebo-subtracted) of their initial body weight by the end of 6 months to 1 year of treatment on that dose of MERIDIA.
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If a patient has not lost at least 4 pounds in the first 4 weeks of treatment, the doctor should consider reevaluation of therapy which may include increasing the dose or discontinuation of MERIDIA.
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, diabetes, dyslipidemia, controlled hypertension).

